M. Dubois

EARLY AND MID-GESTATION ZIKA VIRUS (ZIKV) INFECTION IN THE OLIVE BABOON (PAPIO ANUBIS) LEADS TO FETAL CNS PATHOLOGY BY TERM GESTATION

This study examines ZIKV infection in Olive baboons during early and mid-gestation, finding fetal CNS pathology by term gestation despite resolved viremia.

The prostate cancer therapy enzalutamide compared with abirateroneacetate/prednisone impacts motivation for exploration, spatial learning andalters dopaminergic transmission in aged castrated mice

This study compares the effects of enzalutamide and abiraterone acetate/prednisone on cognitive and dopaminergic functions in aged castrated mice, finding ENZ reduces exploratory behavior and dopaminergic activity.

The Arabidopsis F-box protein FBW2 degrades AGO1 to avoid spurious loading of illegitimate small RNA

This study shows that FBW2 degrades AGO1 to prevent off-target RNA silencing by avoiding illegitimate small RNA loading.

Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans

This study identifies age-related alterations in basal lipid metabolism of naive CD8+ T cells in elderly humans, which impair their function and can be partially reversed with lipid-altering drugs.

Distinct Cellular Strategies Determine Sensitivity to Mild Drought of Arabidopsis Natural Accessions

This paper identifies distinct cellular strategies in Arabidopsis accessions that determine their sensitivity to mild drought, highlighting stomatal closure and cell expansion as key factors.

Adrenomedullin-CALCRL Axis Controls Relapse-Initiating Drug Tolerant Acute Myeloid Leukemia Cells

The paper identifies the ADM-CALCRL axis as a driver of drug-tolerant AML cells that persist after chemotherapy and proposes it as a therapeutic target to prevent relapse.

Early mannitol-triggered changes in the Arabidopsis leaf (phospho)proteome

The paper analyzes early proteome and phosphoproteome changes in Arabidopsis under mild mannitol stress and identifies AHA2 and CRRSP38 as novel regulators of shoot growth under osmotic stress.