Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
C. Podrini, S. Clerici, L. Tronci…·A. Boletta
This study shows that inhibiting asparagine synthetase (ASNS) with antisense oligonucleotides reduces kidney volume and improves renal function in PKD mice by targeting metabolic pathways.
A. Burr, J. Ji, K. Ozler…·T. Hand
This study shows that high sugar diets impair colonic epithelial regeneration by altering metabolic pathways in intestinal stem cells.
W. K. Ma, D. M. Voss, J. Scharner…·A. Krainer
This paper demonstrates that ASO-based PKM splice-switching therapy inhibits HCC cell growth by converting PKM2 to PKM1, altering glucose metabolism and reducing tumorigenesis.
P. S. Bailey, B. M. Ortmann, J. W. Houghton…·J. A. Nathan
The paper identifies ABHD11 as a mitochondrial hydrolase that protects lipoylated proteins from lipid peroxidation, thereby regulating 2-OG levels and 2-OG DD function.
A. Riedel, J. Swietlik, D. Shorthouse…·J. Shields
This study identifies lactate as a tumor-derived metabolite that reprograms fibroblastic reticular cells in draining lymph nodes, altering their function and similarity to tumor-associated fibroblasts.