Author

A. Tijhuis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. C. J. Spierings· 2 shared F. Foijer· 2 shared A. Simon· 1 shared A. Villunger· 1 shared A.-S. Mace· 1 shared F. Schuler· 1 shared G. Karbon· 1 shared H. Hochegger· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

D. C. J. Spierings

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2 papers

Recent·Most cited

Chronic deregulation of the spindle assembly checkpoint triggers myelosuppression and gastrointestinal atrophy

A. Villunger, G. Karbon, F. Schuler, M. Haschka, M. Drach, R. Sotillo, S. Geley, D. C. J. Spierings, A. Tijhuis, F. Foijer

The paper investigates the effects of chronic SAC activation in mice, finding it causes bone marrow aplasia and intestinal atrophy, with BIM playing a critical role in gastrointestinal cell death.

bioRxiv · Sep 8, 2023 · PreprintCell Biology

Genetic instability from a single S-phase after whole genome duplication

S. Gemble, R. Wardenaar, K. Keuper, N. Srivastava, M. Nano, A.-S. Mace, A. Tijhuis, S. V. Bernhard, D. C. J. Spierings, A. Simon, O. Goundiam, H. Hochegger, M. Piel, F. Foijer, Z. Storchova, R. Basto

This study shows that newly formed tetraploid human cells experience high DNA damage during the first S-phase, leading to abnormal karyotypes and genetic instability.

bioRxiv · Jul 16, 2021Cell Biology