Author

A. Tsalikis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. D. Jenks· 2 shared B. E. TANOS· 2 shared A. Al-Malki· 1 shared A. S. Staszewski· 1 shared A. Shoemark· 1 shared D. Keller· 1 shared E. Hargreaves· 1 shared F. Calvo· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

A. D. Jenks

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dysregulated SASS6 expression promotes increased ciliogenesis and cell invasion phenotypes

E. Hargreaves, A. D. Jenks, A. S. Staszewski, A. Tsalikis, R. Bodoque Villar, M. Arias Garcia, Y. Abdi, A. Al-Malki, Y. Yuan, R. Natrajan, S. Haider, T. Iskratsch, W.-J. Wang, S. Godinho, N. J. Palaskas, , B. E. TANOS

This study shows that overexpression of SAS-6 promotes ciliogenesis and cell invasion through YAP/TAZ pathway activation, linked to poor cancer prognosis.

bioRxiv · Jan 29, 2024 · PreprintCell Biology

Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer

A. D. Jenks, S. Vyse, J. P. Wong, D. Keller, T. Burgoyne, A. Shoemark, M. de la Roche, A. Tsalikis, M. Michaelis, J. Cinatl, P. H. Huang, B. E. Tanos

The paper investigates how primary cilia contribute to kinase inhibitor resistance in cancer by altering cilia structure and function, leading to enhanced hedgehog pathway activation and drug resistance.

bioRxiv · Aug 25, 2017Cell Biology