Author

A. Vallejo-Gracia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

M. Ott· 3 shared A. Cruz· 2 shared E. Verdin· 2 shared I. P. Chen· 2 shared M. Walter· 2 shared B. Schilling· 1 shared C. M. Lu· 1 shared D. Boehm· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

M. Ott

Mutual co-authors in cluster

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3 papers

Recent·Most cited

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

M. Walter, I. P. Chen, A. Vallejo-Gracia, I.-J. Kim, O. Bielska, V. L. Lam, J. M. Hayashi, A. Cruz, S. Shah, J. D. Gross, N. J. Krogan, B. Schilling, M. Ott, E. Verdin

This study identifies SIRT5 as a proviral factor that interacts with SARS-CoV-2 Nsp14, enhancing viral replication and suggesting it as a therapeutic target.

bioRxiv · Jan 4, 2022Microbiology

Novel RT-ddPCR assays for determining the transcriptional profile of SARS-CoV-2

S. Telwatte, N. Kumar, A. Vallejo-Gracia, G. R. Kumar, C. M. Lu, M. Ott, J. K. Wong, S. A. Yukl

This paper develops and validates quantitative RT-ddPCR assays to map SARS-CoV-2 transcription profiles, showing higher copy numbers for 3-end genomic targets in clinical samples.

bioRxiv · Jan 12, 2021 · PreprintMicrobiology

FOXO1 promotes HIV Latency by suppressing ER stress in T cells

A. Vallejo-Gracia, I. P. Chen, R. Perrone, E. Besnard, D. Boehm, E. Battivelli, T. Tezil, K. Krey, K. A. Raymond, P. A. Hull, M. Walter, I. Habrylo, A. Cruz, S. Deeks, S. K. Pillai, , M. Ott

This study shows FOXO1 promotes HIV latency by suppressing ER stress in T cells and identifies pathways to selectively reverse quiescence and reduce viral reservoirs.

bioRxiv · Apr 23, 2020Immunology