Author

I.-J. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Verdin· 3 shared M. Ott· 3 shared M. M. Khalid· 2 shared N. J. Krogan· 2 shared A. Balmain· 1 shared A. Ciling· 1 shared A. Cruz· 1 shared A. M. Syed· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

E. Verdin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

M. M. Khalid, I. Chen, F. S. Soveg, T. Y. Taha, T. Tabata, R. Suryawanshi, A. M. Syed, A. Ciling, M. McCavitt-Malvido, U. Schulze-Gahmen, J. Hayashi, I.-J. Kim, S. W. Fong, J. Batra, G. R. Kumar, , M. Ott

This study shows ORF8 suppresses viral particle production by interacting with Spike and causing Golgi fragmentation, supporting evolutionary pressure to delete ORF8 in SARS-CoV-2 variants.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

SARS-CoV-2 ORF8 limits expression levels of Spike antigen.

I.-J. Kim, Y.-h. Lee, M. M. Khalid, Y. Zhang, M. Ott, E. Verdin

This study identifies ORF8 as a SARS-CoV-2 protein that reduces Spike antigen levels on infected cells, thereby limiting antibody recognition and immune evasion.

bioRxiv · Nov 9, 2022 · PreprintMicrobiology

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

M. Walter, I. P. Chen, A. Vallejo-Gracia, I.-J. Kim, O. Bielska, V. L. Lam, J. M. Hayashi, A. Cruz, S. Shah, J. D. Gross, N. J. Krogan, B. Schilling, M. Ott, E. Verdin

This study identifies SIRT5 as a proviral factor that interacts with SARS-CoV-2 Nsp14, enhancing viral replication and suggesting it as a therapeutic target.

bioRxiv · Jan 4, 2022Microbiology

Regulation of KRAS4A/B splicing in cancer stem cells by the RBM39 splicing complex.

W.-C. Chen, M. D. To, P. M. K. Westcott, R. Delrosario, I.-J. Kim, M. Phillips, Q. Tran, N. Bayani, A. Balmain

This study identifies KRAS4A and KRAS4B splice isoforms with distinct expression patterns in cancer stem cells and shows that targeting KRAS4A splicing is a potential therapeutic strategy in KRAS mutant tumors.

bioRxiv · May 22, 2019 · PreprintCancer Biology