Activity-based profiling of primary brain cells identifies covalent allosteric modulators of HCN channels
Elva Ye, Alberto Russo, Roberta Castelli, Gustav T Westlake, Xuan Jiang, Dillon A Spiro, Sara Quejido, Cassandra L. Henry, Jacqueline L. Blankman, Gabriel M. Simon, Bruno N. Melillo, Bina Santoro, Anna Moroni, Benjamin F. Cravatt
bioRxiv · Aug 26, 2026 · PreprintBiochemistry