Min Gao

Prevention of prion disease symptoms in mice with deep PrP lowering

This study demonstrates that deep PrP lowering with a potent siRNA prevents prion disease symptoms in mice and extends survival in symptomatic animals.

A retinal adrenergic module tunes mammalian visual evolution

The paper identifies an evolutionarily mobile adrenergic module in the mammalian retina that modulates visual function across species.

Comprehensive characterization of V(D)J recombination from long-read transcriptomic data with VDJcraft

VDJcraft is a pipeline for analyzing V(D)J recombination from long-read transcriptome data, showing improved accuracy and novel gene subclass discovery.

Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC-I deficient solid tumors

This paper shows that IL-21-Fc reprograms NK cell metabolism to enhance their function against MHC-I deficient tumors, leading to tumor eradication in preclinical models.

Transplanting ANXA1- CD8+ Naive T cells Delay Aging Through Senolysis

This study shows that transplanting ANXA1-negative CD8 naive T cells extends lifespan and improves health in aged mice by reducing senescence.

VlbZIP30 of grapevine functions in drought tolerance via the abscisic acid core signaling pathway

This study identifies VlbZIP30 as a positive regulator of drought tolerance in grapevines by modulating 27 candidate genes through the ABA core signaling pathway.