Author

Andrew Chang

The University of Sydney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jialing ZhangiD· 2 shared Jianhai DuiD· 2 shared Mark C. GilliesiD· 2 shared Meidong ZhuiD· 2 shared Michelle YamiD· 2 shared Shaoxue ZengiD· 2 shared Sora LeeiD· 2 shared Yue Zeng· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersNeuroscience

Jialing ZhangORCID

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Author profile →

2 papers

Recent·Most cited

Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Muller Cells

Ting Zhang, Kaiyu Jin, Shaoxue Zeng, Penghui Yang, Meidong Zhu, Jialing Zhang, Yingying Chen, Sora Lee, Michelle Yam, Yue Zeng, Xiaoyan Lu, Lipin Loo, G. Gregory Neely, Andrew Chang, Fanfan Zhou, , Mark C. Gillies

The paper identifies differences in stress response and function between macular and peripheral Muller cells, linking these differences to vulnerability to degenerative diseases.

Redox Biology · May 24, 2025Peer-reviewedNeuroscience

Dysregulated Proline Metabolism Contributes to Subretinal Fibrosis in Neovascular AMD: Therapeutic Potential of Prolyl-4-Hydroxylase Inhibition

Yue Zeng, Ting Zhang, Elisa Eleanor Cornish, Sora Lee, Michelle Yam, Mark Eminhizer, Jingwen Zeng, Jialing Zhang, Shaoxue Zeng, Xian Wei, Jinliang Yang, Meidong Zhu, Andrew Chang, Meixia Zhang, Jianhai Du, , Mark C. Gillies

This study identifies proline metabolism, specifically proline hydroxylation via P4HA1, as a driver of subretinal fibrosis in nAMD and shows that P4HA1 inhibition reduces fibrosis in mouse models.

bioRxiv · Apr 13, 2025 · PreprintNeuroscience