Author

Fanfan Zhou

The University of SydneyORCID 0000-0002-1982-1541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jianhai DuiD· 2 shared Ling ZhuiD· 2 shared Meidong ZhuiD· 2 shared Michelle YamiD· 2 shared Sora LeeiD· 2 shared Andrew Chang· 1 shared Fang Lu· 1 shared G. Gregory NeelyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jianhai DuORCID

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3 papers

Recent·Most cited

Lateral opening site of human oligopeptide transporter 2 plays a key role in the interaction with polymyxins

Xukai Jiang, Yining Luo, Mohammad A. K. Azad, Limei Xu, Min Xiao, Tony Velkov, Kade D. Roberts, Visanu Thamlikitkul, Qi Tony Zhou, Fanfan Zhou, Jian Li

This study identifies key residues in hPepT2 involved in polymyxin interaction, showing that modifying these residues reduces nephrotoxicity while maintaining antibacterial activity.

eLife · Oct 29, 2026Peer-reviewedBiochemistry

Role of Alanine Transaminase in Retinal Metabolic Homeostasis: Potential therapeutic target in retinal diseases

Qin Chen, Ting Zhang, Jingwen Zeng, Michelle Yam, Sora Lee, Fanfan Zhou, Meidong Zhu, Ming Zhang, Fang Lu, Jianhai Du, Mark Gillies, Ling Zhu

This study investigates the role of alanine transaminase (ALT) in human neural retina metabolism, showing its involvement in carbon/nitrogen flux and redox balance, with potential therapeutic implications for retinal diseases.

bioRxiv · Apr 22, 2026 · PreprintNeuroscience

Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Muller Cells

Ting Zhang, Kaiyu Jin, Shaoxue Zeng, Penghui Yang, Meidong Zhu, Jialing Zhang, Yingying Chen, Sora Lee, Michelle Yam, Yue Zeng, Xiaoyan Lu, Lipin Loo, G. Gregory Neely, Andrew Chang, Fanfan Zhou, , Mark C. Gillies

The paper identifies differences in stress response and function between macular and peripheral Muller cells, linking these differences to vulnerability to degenerative diseases.

Redox Biology · May 24, 2025Peer-reviewedNeuroscience