Author

Anne Valade

UCB Pharma (Belgium)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Organism:rat· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Andrea VarroneiD· 3 shared Anton Forsberg Morén· 3 shared Hans ÅgreniD· 3 shared Rongfeng ZouiD· 3 shared Sangram NagiD· 3 shared C. Vermeiren· 2 shared Christer HalldiniD· 2 shared Elena PedergnanaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Andrea VarroneORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Imaging Synaptic Vesicle Protein SV2C with 18F-UCB-F: An In Vitro Autoradiography and In Vivo NHP PET Study

Sangram Nag, V. C. Sousa, Rongfeng Zou, Anton Forsberg Morén, P. Datta, Y. Khani, Anne Valade, C. Vermeiren, P. Motte, J Mercier, Hans Ågren, C Halldin, Andrea Varrone

This study evaluates [18F]UCB-F as a PET radioligand for imaging SV2C, finding it unsuitable due to poor in vivo stability and brain retention.

ACS Chemical Neuroscience · Jun 26, 2026Peer-reviewedNeuroscience

In silico evaluation of the effects of temperature on the affinity of the SV2C ligand UCB-1A to SV2 isoforms

Rongfeng Zou, Sangram Nag, Vasco C. Sousa, Anton Forsberg Morén, Miklós Tóth, Yasir Khani Meynaq, Elena Pedergnana, Anne Valade, C. Vermeiren, P. Motte, J Mercier, Xiaoqun Zhang, Per Svenningsson, Christer Halldin, Andrea Varrone, Hans Ågren

This study evaluates how temperature affects UCB-1A binding to SV2A and SV2C using experimental assays and molecular dynamics simulations, finding that binding to SV2C remains stable while SV2A shows temperature sensitivity.

bioRxiv · Mar 21, 2026 · PreprintBiochemistry

Discovery and characterization of UCB-1A: the first PET radioligand for imaging synaptic vesicle glycoprotein 2C

Sangram Nag, Vasco C. Sousa, Anton Forsberg Morén, Miklós Tóth, Yasir Khani Meynaq, Elena Pedergnana, Rongfeng Zou, Anne Valade, Céline Vermeiren, Philippe Motté, Joël Mercier, Xiaoqun Zhang, Per Svenningsson, Hans Ågren, Christer Halldin, Andrea Varrone

This paper develops UCB-1A, the first PET radioligand for imaging SV2C, showing it binds selectively to SV2C in brain regions and is suitable for Parkinson's disease studies.

bioRxiv · Mar 10, 2026 · PreprintNeuroscience