Author

Aravind R. Gade

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:electrophysiology· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Geoffrey S. PittiD· 4 shared Maiko MatsuiiD· 3 shared Isabella A. DiStefanoiD· 2 shared Keon Mazdisnian· 2 shared Lala Tanmoy DasiD· 2 shared Mattia MalvezziiD· 2 shared Steven O. MarxiD· 2 shared Allison GalanteiD· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBiophysics

Geoffrey S. PittORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding

Aravind R. Gade, Mattia Malvezzi, Lala Tanmoy Das, Maiko Matsui, Cheng-I Jonathan Ma, Keon Mazdisnian, Steven O. Marx, Frederick R. Maxfield, Geoffrey S. Pitt

This study shows FGF13 modulates VGSCs by regulating membrane cholesterol, independent of direct channel binding, and reveals its role in maintaining cholesterol distribution and VGSC localization at the intercalated disc.

Journal of Clinical Investigation · Aug 12, 2025Peer-reviewedBiophysics

FGF13 regulates cardiomyocyte impulse propagation via Cx43 trafficking independent of voltage-gated sodium channels

Lala Tanmoy Das, Mattia Malvezzi, Aravind R. Gade, Maiko Matsui, Margaret McKay, Qian Wei, Matea J. Zelich, Keon Mazdisnian, Jared Kushner, Bi-xing Chen, Isabella A. DiStefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C. Lo, , Geoffrey S. Pitt

This study shows FGF13 regulates Cx43 trafficking and cardiac impulse propagation without involving voltage-gated sodium channels.

bioRxiv · Jul 23, 2025 · PreprintPhysiology

Macromolecular interactions dictate Polycomb-mediated epigenetic repression

Christian Much, Sandy M. Rajkumar, Liming Chen, John M. Cohen, Aravind R. Gade, Geoffrey S. Pitt, Yicheng Long

The paper investigates the distinct roles of PRC2 subcomplexes in epigenetic repression and stem cell differentiation using human pluripotent stem cells.

bioRxiv · May 15, 2025 · PreprintMolecular Biology

Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism

Susan Lin, Aravind R. Gade, Hong-Gang Wang, James E. Niemeyer, Allison Galante, Isabella A. DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H. Schwartz, Anjali M. Rajadhyaksha, Geoffrey S. Pitt

This study identifies FGF13's role in seizure susceptibility through interneuron-specific knockout mice, revealing a sodium channel-independent mechanism involving K+ channel regulation.

eLife · Jan 8, 2025Peer-reviewedNeuroscience