Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism
Susan Lin, Aravind R. Gade, Hong-Gang Wang, James E. Niemeyer, Allison Galante, Isabella A. DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H. Schwartz, Anjali M. Rajadhyaksha, Geoffrey S. Pitt
This study identifies FGF13's role in seizure susceptibility through interneuron-specific knockout mice, revealing a sodium channel-independent mechanism involving K+ channel regulation.
eLife · Jan 8, 2025Peer-reviewedNeuroscience