Author

Ashley Scheutzow

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam KlaissiD· 1 shared Alexander D. SorkiniD· 1 shared Asa W. Huffaker· 1 shared Gracie SifferiD· 1 shared Janine KirsteiniD· 1 shared Kunal GharatiD· 1 shared Mary E. SkinneriD· 1 shared Matthew J. O’MearaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Adam KlaissORCID

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Author profile →

2 papers

Recent·Most cited

HSP-1-Specific Nanobodies Alter Chaperone Function in vitro and in vivo

Nicholas D. Urban, Kunal Gharat, Zachary Mattiola, Ashley Scheutzow, Adam Klaiss, Sarah Tabler, Asa W. Huffaker, Monique Grootveld, Mary E. Skinner, Weiyang Zheng, Matthew J. O’Meara, Janine Kirstein, Matthias C. Truttmann

This study develops two nanobodies that specifically target HSP-1, reducing its ATPase activity and protein folding capacity both in vitro and in vivo.

Journal of Biological Chemistry · Feb 4, 2026Peer-reviewedBiochemistry

E3 ligase recruitment by UBQLN2 protects substrates from proteasomal degradation

Ashley Scheutzow, Sachini Thanthirige, Gracie Siffer, Alexander D. Sorkin, Matthew L. Wohlever

This study shows UBQLN2 stabilizes substrates by recruiting E3 ligases, which promotes phase separation and protects against proteasomal degradation, and this mechanism is disrupted in ALS mutants.

bioRxiv · Jul 4, 2024 · PreprintBiochemistry