Author

Pragallabh Purwar

University of Geneva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alan GerberiD· 1 shared Alberto J. ArribasiD· 1 shared Alex A. HennemaniD· 1 shared Amandine Pradier· 1 shared Astrid Melotti· 1 shared Aurélien PommieriD· 1 shared Bart A. WestermaniD· 1 shared Carole BourquiniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

Alan GerberORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of 3-mercaptopyruvate sulfurtransferase enhances CD8⁺ T-cell antitumor immunity

Muriel Urwyler, Marietta Margaréta Korsós, Eloïse Dupuychaffray, Nikita Markov, Kelly Ascenção, Maria Petrosino, Karim Zuhra, Darko Stojkov, Sara Barcos, Jérémie Tachet, Pragallabh Purwar, Montserrat Alvarez, Aurélien Pommier, Mohamed Zakaria Gad, Reham M. Abdel-Kader, , Carole Bourquin

This study shows that inhibiting 3-MST reduces H2S in renal cell carcinoma, enhances T cell activation, and boosts antitumor immunity.

Redox Biology · Aug 28, 2026Peer-reviewedPharmacology & Toxicology

EGFR upregulation drives signaling reactivation during EGFR inhibition in glioblastoma without broad kinome rewiring

Yoran Broersma, Megan Houweling, Tsz Ting Wong, Pragallabh Purwar, Richard R. de Haas, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Connie R. Jiménez, David P. Noske, Alan Gerber, Bart A. Westerman

This study shows that EGFR inhibition in glioblastoma does not lead to broad kinome rewiring but instead results in increased EGFR abundance and partial restoration of EGFR signaling.

bioRxiv · Aug 18, 2026 · PreprintCancer Biology

Ibrutinib modulates CD19 expression and improves efficacy of CD19-CAR T cells in B-cell lymphoma models

Sisi Wang, Alberto J. Arribas, Chiara Tarantelli, Elisa Civanelli, Guangyu Zhou, Pragallabh Purwar, Amandine Pradier, Astrid Melotti, Francesca Guidetti, Yara Hajj Younes, Lodovico Terzi di Bergamo, Luciano Cascione, Sara Napoli, Emanuele Zucca, Elena Sotillo, , Francesco Bertoni

The paper shows ibrutinib increases CD19 expression in B-cell lymphoma models, improving the effectiveness of CD19-CAR T cells.

bioRxiv · May 26, 2026 · PreprintImmunology