Author

B. Cubitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant calling· 1

Frequent Co-Authors

J. C. de la Torre· 3 shared H. Witwit· 2 shared A. Kim· 1 shared A. O. Kamphorst· 1 shared A. Salaniwal· 1 shared B. Davenport· 1 shared C. Ye· 1 shared D. Choo· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

J. C. de la Torre

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3 papers

Recent·Most cited

Functional impairment of "helpless" CD8+ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

V. van der Heide, B. Davenport, B. Cubitt, V. Roudko, D. Choo, E. Humblin, K. Jhun, K. Angeliadis, T. Dawson, G. Furtado, A. O. Kamphorst, R. Ahmed, J. C. de la Torre, D. Homann

This study shows that helpless CD8+ memory T cells, which form without CD4+ help, have transient functional impairments due to prolonged antigen exposure, which resolve over time.

bioRxiv · Jan 22, 2024Immunology

Activation of Protein Kinase R (PKR) Plays a Pro-Viral Role in Mammarenavirus Infected Cells

H. Witwit, R. Khafaji, A. Salaniwal, A. Kim, B. Cubitt, C. Ye, N. Jackson, S. R. Weiss, L. Martinez-Sobrido, J. C. de la Torre

This study shows that PKR activation can both restrict and enhance LCMV replication, revealing a complex role for PKR in mammarenavirus infection.

bioRxiv · Dec 5, 2023Microbiology

Inhibitors of anti-apoptotic Bcl-2 family proteins exhibit potent and broad-spectrum anti-mammarenavirus activity via cell cycle arrest at G0/G1 phase

Y.-J. Kim, H. Witwit, B. Cubitt, J. C. de la Torre

This paper shows Bcl-2 inhibitors like ABT-737 and OLX block mammarenavirus and SARS-CoV-2 by causing G0/G1 cell cycle arrest, not through apoptosis.

bioRxiv · Aug 16, 2021Microbiology