Author

B. E. Sleebs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

P. R. Gilson· 4 shared B. S. Crabb· 3 shared M. G. Dans· 3 shared A. E. Barry· 2 shared D. B. Ling· 2 shared H. E. Bullen· 2 shared O. Looker· 2 shared T. F. de Koning-Ward· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCell Biology

P. R. Gilson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1

M. G. Dans, C. Boulet, G. M. Watson, W. Nguyen, J. M. Dziekan, C. Evelyn, K. Reaksudsan, S. Mehra, Z. Razook, N. D. Geoghegan, M. J. Mlodzianoski, C. D. Goodman, D. B. Ling, T. K. Jonsdottir, J. Tong, , P. R. Gilson

The paper identifies aryl amino acetamides that inhibit Plasmodium falciparum ring development by targeting PfSTART1, a lipid transfer protein, and shows these inhibitors block parasite transmission.

bioRxiv · Nov 2, 2023 · PreprintCell Biology

A pyridyl-furan series developed from Open Global Health Library blocks red blood cell invasion and protein trafficking in Plasmodium falciparum through potential inhibition of the parasites PI4KIIIb enzyme.

D. B. Ling, W. Nguyen, O. Looker, Z. Razook, K. McCann, A. E. Barry, C. Scheurer, S. Wittlin, H. E. Bullen, B. S. Crabb, B. E. Sleebs, P. R. Gilson

The paper identifies a pyridyl-furan compound series that inhibits Plasmodium falciparum growth and red blood cell invasion by targeting the PI4KIIIb enzyme.

bioRxiv · Apr 25, 2023Microbiology

The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites

O. Looker, M. G. Dans, H. E. Bullen, B. E. Sleebs, B. S. Crabb, P. R. Gilson

The paper screens 400 anti-malarial compounds to identify inhibitors of protein export in Plasmodium falciparum, finding MMV396797 as a potent inhibitor that reduces parasite virulence.

bioRxiv · May 1, 2022Biochemistry

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds

M. G. Dans, G. E. Weiss, D. W. Wilson, B. E. Sleebs, B. Crabb, T. F. de Koning-Ward, P. R. Gilson

The paper screens a compound library to identify inhibitors of Plasmodium falciparum egress and invasion, finding several compounds with specific inhibitory effects.

bioRxiv · Sep 13, 2019Cell Biology