Author

B. J. Arachchige

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. X. Foo· 2 shared H. Bielefeldt-Ohmann· 2 shared K. Ronacher· 2 shared M. D. Ngo· 2 shared M. M. Rosenkilde· 2 shared S. Bartlett· 2 shared A. Khromykh· 1 shared B. Matthews· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

C. X. Foo

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Author profile →

2 papers

Recent·Most cited

Oxysterols drive inflammation via GPR183 during influenza virus and SARS-CoV-2 infection

C. X. Foo, S. Bartlett, K. Y. Chew, M. D. Ngo, H. Bielefeldt-Ohmann, B. J. Arachchige, B. Matthews, S. Reed, R. Wang, M. J. Sweet, L. Burr, J. E. Sinclair, R. Parry, A. Khromykh, K. R. Short, , K. Ronacher

This study identifies oxysterols and GPR183 as drivers of inflammation in the lung during influenza and SARS-CoV-2 infections, showing that targeting GPR183 reduces inflammation and disease severity.

bioRxiv · Jun 14, 2022Immunology

A blunted GPR183/oxysterol axis during dysglycemia results in delayed recruitment of macrophages to the lung during M. tuberculosis infection

M. D. Ngo, S. Bartlett, H. Bielefeldt-Ohmann, C. X. Foo, R. Sinha, B. J. Arachchige, S. J. Reed, T. Mandrup-Poulsen, M. M. Rosenkilde, K. Ronacher

This study shows that dysglycemia impairs the GPR183/oxysterol axis, leading to delayed macrophage recruitment and worsened tuberculosis outcomes in mice.

bioRxiv · Jan 5, 2022Immunology