B. R. King

Drug-induced adaptation along a resistance continuum in cancer cells

This study shows that gradual dose exposure and prolonged treatment drive ovarian cancer cell resistance to targeted therapy through a continuous adaptation process involving transcriptional, epigenetic, and genetic changes.

Microtubule associated proteins and motors required for ectopic microtubule array formation in S. cerevisiae

The paper identifies microtubule-associated proteins and motors essential for forming ectopic microtubule arrays in yeast by using a novel inducible nucleation site.

XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions

This study investigates whether XMAP215 and γ-tubulin synergize in microtubule nucleation and finds they act additively, not synergistically, in purified solutions.