Author

M. Latorre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. D. Humphrey· 3 shared A. W. Caulk· 2 shared S.-I. Murtada· 2 shared A. B. Ramachandra· 1 shared A. R. Flores· 1 shared A. Rojas· 1 shared B. Jiang· 1 shared B. Spronck· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

J. D. Humphrey

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Author profile →

4 papers

Recent·Most cited

Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus.

S. DebRoy, V. A. Tobar, G. Galvez, S. Arora, X. Liang, N. M. Horstmann, V. Maracaja-Coutinho, M. Latorre, M. Hook, A. R. Flores, S. Shelburne

This study identifies the in vivo DNA binding profile of CcpA in group A Streptococcus and shows that HPr is required for CcpA-mediated regulation and DNA binding.

Molecular Microbiology · Jun 1, 2021Peer-reviewedMicrobiology

Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice

B. Spronck, M. Latorre, S. Mehta, A. W. Caulk, A. B. Ramachandra, S.-I. Murtada, A. Rojas, C.-S. He, B. Jiang, M. Wang, M. R. Bersi, G. Tellides, J. D. Humphrey

This study shows that genetic background strain influences aortic fibrosis in hypertensive mice, with C57BL/6J mice showing more maladaptive remodeling than 129SvEv mice.

bioRxiv · May 5, 2020Bioengineering

Fast, Rate-Independent, Finite Element Implementation of a 3D Constrained Mixture Model of Soft Tissue Growth and Remodeling

M. Latorre, J. D. Humphrey

This paper introduces a fast finite element implementation of a 3D constrained mixture model for simulating soft tissue growth and remodeling, showing quadratic convergence and applications to aortic aneurysm enlargement.

bioRxiv · Feb 27, 2020Bioengineering

Paradoxical Aortic Stiffening and Subsequent Cardiac Dysfunction in Hutchinson-Gilford Progeria Syndrome

S.-I. Murtada, Y. Kawamura, A. W. Caulk, H. Ahmadzadeh, N. Mikush, K. Zimmerman, D. Kavanagh, D. Weiss, M. Latorre, Z. W. Zhuang, G. S. Shadel, D. T. Braddock, J. D. Humphrey

This study shows that aortic stiffening and cardiac dysfunction in HGPS mice occur due to loss of smooth muscle function and proteoglycan accumulation, independent of sex, with potential therapeutic implications.

bioRxiv · Oct 2, 2019Bioengineering