Author

B.-S. Shin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

J. Wang· 3 shared C. Alvarado· 2 shared J. D. Puglisi· 2 shared T. E. Dever· 2 shared C. P. Lapointe· 1 shared C. S. Fraser· 1 shared E. Montabana· 1 shared I. Fernandez· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

J. Wang

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Author profile →

3 papers

Recent·Most cited

eIF5B and eIF1A remodel human translation initiation complexes to mediate ribosomal subunit joining

C. P. Lapointe, R. Grosely, M. Sokabe, C. Alvarado, J. Wang, E. Montabana, N. Villa, B.-S. Shin, T. E. Dever, C. S. Fraser, I. S. Fernandez, J. D. Puglisi

This study uses single-molecule techniques and cryo-EM to show how eIF1A and eIF5B remodel initiation complexes to facilitate ribosomal subunit joining during translation initiation.

bioRxiv · Dec 9, 2021Biophysics

Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation

J. Wang, C. Alvarado, B.-S. Shin, J. Bohlen, T. E. Dever, J. D. Puglisi

The paper directly observes yeast 43S ribosomal scanning along mRNA 5'UTRs, revealing its speed and structural regulation mechanisms.

bioRxiv · Dec 8, 2021Biophysics

Large ribosomal subunit, eIF5B, Met-tRNAiMet and mRNA cooperate to complete accurate initiation.

J. Wang, J. Wang, B.-s. Shin, T. Dever, J. Puglisi, I. Fernandez

The paper determines the cryoEM structure of a long-lived translation initiation intermediate involving eIF5B, Met-tRNAiMet, and the ribosome post GTP hydrolysis.

bioRxiv · May 30, 2020Biochemistry