Author

E. Montabana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. K. Kobilka· 2 shared C. Habrian· 2 shared E. Y. Isacoff· 2 shared H. Wang· 2 shared N. R. Latorraca· 2 shared S. Marqusee· 2 shared A. Koehl· 1 shared B.-S. Shin· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiophysics

B. K. Kobilka

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Step-wise activation of a Family C GPCR

K. K. Kumar, H. Wang, C. Habrian, N. R. Latorraca, J. Xu, E. S. O'Brien, C. Zhang, E. Montabana, A. Koehl, S. Marqusee, E. Y. Isacoff, B. K. Kobilka

The paper proposes a step-wise activation model for metabotropic glutamate receptor subtype 5, supported by structural and fluorescence imaging data of different activation states.

bioRxiv · Aug 29, 2023 · PreprintBiophysics

Negative allosteric modulation of the glucagon receptor by RAMP2

K. Krishna Kumar, E. O'Brien, C. Habrian, N. R. Latorraca, H. Wang, I. Tuneew, E. Montabana, S. Marqusee, D. Hilger, E. Y. Isacoff, J. M. Mathiesen, B. K. Kobilka

This study shows RAMP2 inhibits GCGR signaling by inducing conformational changes and disorder in the receptor's extracellular domain.

bioRxiv · Aug 30, 2022 · PreprintBiochemistry

eIF5B and eIF1A remodel human translation initiation complexes to mediate ribosomal subunit joining

C. P. Lapointe, R. Grosely, M. Sokabe, C. Alvarado, J. Wang, E. Montabana, N. Villa, B.-S. Shin, T. E. Dever, C. S. Fraser, I. S. Fernandez, J. D. Puglisi

This study uses single-molecule techniques and cryo-EM to show how eIF1A and eIF5B remodel initiation complexes to facilitate ribosomal subunit joining during translation initiation.

bioRxiv · Dec 9, 2021Biophysics

Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule

W. Li, F. R. Ward, K. McClure, S. T. Chang, E. Montabana, S. Liras, R. Dullea, J. Cate

This study identifies how PF-846 selectively stalls ribosome translation by binding in a specific pocket and altering nascent chain path, revealing a mechanism for targeted protein inhibition.

bioRxiv · Jan 9, 2019Biophysics