Author

Billy Nguyen

Rush University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Vineet GuptaiD· 2 shared Viviana JiméneziD· 2 shared Ameera M. ShawiD· 1 shared Antonio Barbosa· 1 shared Bryan A. KillingeriD· 1 shared Chang‐Woo LeeiD· 1 shared Darlah M. López-RodrígueziD· 1 shared David Changli Wei· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Vineet GuptaORCID

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Author profile →

3 papers

Recent·Most cited

CD11b Activation Reduces Myeloid Brain Infiltration and Mitigates Synucleinopathy in a Model of Parkinson's Disease

Ameera M. Shaw, Viviana Jiménez, Billy Nguyen, Jayda B. Duvernay, Solji G. Choi, Mike Cameron, Bryan A. Killinger, Vineet Gupta

This study shows that CD11b agonism with LA1 reduces microglial activation and myeloid cell infiltration, thereby mitigating synucleinopathy in a Parkinson's disease model.

bioRxiv · Aug 11, 2025 · PreprintNeuroscience

CD11b suppresses TLR7-driven inflammatory signaling to protect against lupus nephritis

Xiaobo Li, Veronica Villanueva, Viviana Jiménez, Billy Nguyen, Nishant Ranjan Chauhan, Samia Q. Khan, Jessica M. Dorschner, Mark A. Jensen, Khulood A. Alzahrani, Wei HuiTing, David J. Cimbaluk, David Changli Wei, Meenakshi Jolly, Darlah M. López-Rodríguez, Santiago Balza Pineda, , Vineet Gupta

This study shows that CD11b activation reduces TLR7-driven inflammation and protects against lupus nephritis through mechanisms involving suPAR suppression and immune complex reduction.

bioRxiv · Jul 26, 2024 · PreprintImmunology

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Leon Tejwani, Neal G. Ravindra, Chang‐Woo Lee, Yubao Cheng, Billy Nguyen, Kimberly P. Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John T. Gionco, Yangfei Xiang, Jennifer Yoon, Hannah J. Ro, Fatema Haidery, Rosalie M. Grijalva, , Janghoo Lim

This study uses longitudinal single-nucleus RNA sequencing to analyze transcriptional dynamics in SCA1 cerebellum, identifying early cellular changes and applying deep learning to predict disease state.

Neuron · Nov 27, 2023Peer-reviewedNeuroscience