Author

C. Espinoza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

F. Bednar· 2 shared F. Lima· 2 shared M. Pasca di Magliano· 2 shared P. Kadiyala· 2 shared T. L. Frankel· 2 shared W. Du· 2 shared Y. Zhang· 2 shared A. Amato· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

F. Bednar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice

I. Barravecchia, J. M. Lee, J. Manassa, B. Magnuson, S. Cavanaugh, N. G. Steele, C. Espinoza, C. J. Galban, N. Ramnath, T. L. Frankel, M. Pasca di Magliano, S. Galban

This study develops a mouse model to investigate how IPF-related fibrosis influences lung cancer development and identifies immune-suppressive mechanisms and therapeutic targets.

bioRxiv · Jun 20, 2023Cancer Biology

Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early pre-neoplastic pancreatic lesions

E. S. Carpenter, A. M. Elhossiny, P. Kadiyala, J. Li, J. McGue, B. Griffith, Y. Zhang, J. Edwards, S. Nelson, F. Lima, K. L. Donahue, W. Du, A. C. Bischoff, D. Alomari, H. Watkoske, , M. Pasca Di Magliano

The paper analyzes donor pancreata to define the transcriptomic signature and microenvironment of early pre-neoplastic lesions, finding PanIN lesions are common in healthy individuals and show transcriptional similarity to cancer cells.

bioRxiv · Jan 13, 2023 · PreprintCancer Biology

Arginase 1 is a key driver of immune suppression in pancreatic cancer

R. E. Menjivar, Z. C. Nwosu, W. Du, K. Donahue, C. Espinoza, K. Brown, A. Velez, W. Yan, F. Lima, A. Bischoff, P. Kadiyala, D. Salas-Escabillas, C. J. Halbrook, F. Bednar, E. Carpenter, , M. di Magliano

This study shows that Arginase 1 suppresses immune responses in pancreatic cancer by inhibiting T cell activation, and targeting it enhances immunotherapy effectiveness.

bioRxiv · Jun 21, 2022Cancer Biology

The grape MYB24 mediates the coordination of light-induced terpene and flavonol accumulation in response to berry anthocyanin sunscreen depletion

C. Zhang, Z. Dai, T. Ferrier, L. Orduna, A. Santiago, A. Peris, D. Wong, C. Kappel, S. Savoi, R. Loyola, A. Amato, B. Kozak, M. Li, D. Carrasco, C. Meyer, , J. T. Matus

The paper identifies MYB24 as a transcription factor coordinating light-induced terpene and flavonol accumulation in response to anthocyanin depletion in grape berries.

bioRxiv · Dec 16, 2021 · PreprintPlant Biology