Author

C. Frankfater

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

F.-f. Hsu· 2 shared K. Zhang· 2 shared A. Mauguen· 1 shared C. Cardoso· 1 shared C. Haram· 1 shared D. R. Spitz· 1 shared E. Nunez· 1 shared F. M. Kuhlmann· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

F.-f. Hsu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sphingolipids protect ergosterol in the Leishmania major membrane from sterol-binding toxins

C. Haram, S. Moitra, R. Keane, F. M. Kuhlmann, C. Frankfater, F.-f. Hsu, S. M. Beverley, K. Zhang, P. A. Keyel

This study investigates how sphingolipids in Leishmania major protect ergosterol from sterol-binding toxins, showing that ceramide reduces toxin cytotoxicity and enhances amphotericin B efficacy.

bioRxiv · Jun 15, 2022Microbiology

Sex Differences in Brain Tumor Glutamine Metabolism Reveal Sex-Specific Vulnerabilities to Treatment

J. Sponagel, J. K. Jones, C. Frankfater, S. Zhang, O. Tung, K. Cho, K. L. Tinkum, H. Gass, E. Nunez, D. R. Spitz, P. Chinnaiyan, J. Schaefer, G. J. Patti, M. S. Graham, A. Mauguen, , J. E. Ippolito

The paper identifies sex differences in glutamine metabolism in glioblastomas, showing male tumors have higher glutamine uptake and are more sensitive to GLS1 inhibition than female tumors.

bioRxiv · Sep 29, 2021Cancer Biology

Lathosterol oxidase (sterol C5-desaturase) deletion confers resistance to amphotericin B and sensitivity to acidic stress in Leishmania major

Y. Ning, C. Frankfater, F.-F. Hsu, R. Soares, C. Cardoso, P. Nogueira, N. Lander, R. Docampo, K. Zhang

This study shows that deleting LSO in Leishmania major confers amphotericin B resistance but causes sensitivity to acidic stress and membrane disruption.

bioRxiv · Apr 20, 2020Microbiology