Author

C. G. Pfeifer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

K. B. Choi· 4 shared L. Munro· 3 shared W. A. Jefferies· 3 shared H. Arora· 2 shared I. Saranchova· 2 shared S. Kari· 2 shared W. Jefferies· 2 shared C.-J. Lu· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersImmunology

K. B. Choi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An ATP-Binding Cassette Transporter Gene Links Innate and Adaptive Immune Responses

S. Wilcox, H. Arora, K. B. Choi, S. Kari, L. Munro, C. G. Pfeifer, W. A. Jefferies

This study identifies ABCF1 as a critical link between innate and adaptive immunity by regulating OAS1 and RNaseL activity, influencing antiviral responses to SARS-CoV-2 and VSV.

bioRxiv · Dec 31, 2023 · PreprintImmunology

Phagocytosis in macrophages is regulated by the ATP-binding cassette family gene ABCF1

H. Arora, K. B. Choi, L. Munro, C. G. Pfeifer, W. A. Jefferies

This study identifies ABCF1 as a regulator of phagocytosis in macrophages through its role in signaling pathways involving Src family kinases and SYK.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Novel Curcuphenol Analogues Possess Anti-Metastatic Biologic Activity

S. L. S. Ellis, L. L. Nohara, S. Dada, I. Saranchova, L. Munro, K. B. Choi, E. Garrovillas, C. G. Pfeifer, D. E. Williams, P. Cheng, R. J. Andersen, W. Jefferies

The paper develops water-soluble curcuphenol analogues with improved chemical properties that reverse tumour immune-escape mechanisms, reducing metastatic growth.

bioRxiv · May 15, 2023 · PreprintBiochemistry

A Binary RNA and DNA Self-Amplifying Platform for Next Generation Vaccines and Therapeutics

W. Jefferies, K. B. Choi, P. Ribeca, S. Kari, J. Young, E. Hui, S. Y. Qi, E. Garrosvillas, P. Lincez, T. Welch, I. Saranchova, C. G. Pfeifer

This paper introduces a binary RNA and DNA self-amplifying platform that enhances vaccine effectiveness, reduces cost, and simplifies manufacturing and distribution.

bioRxiv · Dec 6, 2022 · PreprintImmunology

Mutation of an L-Type Calcium Channel Gene Leads to a Novel Human Primary Cellular Immunodeficiency

F. Fenninger, S. R. Stanwood, C.-J. Lu, C. G. Pfeifer, O. Khan, N. D. Romberg, R. Herati, E. J. Wherry, K. C. O'Boyle, S. E. Henrickson, K. Maurer, M. A. Ruffner, W. A. Jefferies, K. E. Sullivan

This study identifies a mutation in the Cav1.4 gene causing a primary immunodeficiency with immune dysfunction and recurrent infections.

bioRxiv · Dec 4, 2019 · PreprintImmunology