Author

Y. X. Setoh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. A. Amarilla· 2 shared A. A. Khromykh· 2 shared A. Suhrbier· 2 shared D. Watterson· 2 shared A. Amarilla· 1 shared A. Slonchak· 1 shared C. J. Mycroft-West· 1 shared C. M. Spalluto· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

A. A. Amarilla

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Establishment of a CPER Reverse Genetics System for Powassan Virus Defines Attenuating NS1 Glycosylation Sites and an Infectious NS1-GFP11 Reporter Virus

J. N. Conde, G. E. Himmler, M. C. Mladinich, Y. X. Setoh, A. A. Amarilla, W. R. Schutt, N. Saladino, E. E. Gorbunova, D. J. Salamango, E. Wimmer, H. K. Kim, E. R. Mackow

This paper establishes a reverse genetics system for Powassan virus, identifies attenuating NS1 glycosylation sites, and creates an infectious NS1-GFP11 reporter virus to study viral functions.

bioRxiv · May 3, 2023Microbiology

Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis

A. Slonchak, X. Wang, H. Chaggar, J. Aguado, M. Freney, K. Yan, F. J. Torres, A. A. Amarilla, R. Balea, J. D. J. Sng, Y. X. Setoh, N. Peng, D. Watterson, E. Wolvetang, A. Suhrbier, A. A. Khromykh

This study identifies how ZIKV sfRNA interacts with NS5 to inhibit STAT1 phosphorylation, promoting viral pathogenesis in placental and neural tissues.

bioRxiv · May 18, 2021Microbiology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology