Author

C. McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pathology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. K. Ponti· 2 shared B. DeLucia· 2 shared E. E. Johnson· 2 shared J. Claesen· 2 shared L. J. Osborn· 2 shared M. T. Zangara· 2 shared S. Jatana· 2 shared A. J. Horak· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

A. K. Ponti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Inhibition of pyrimidine synthesis in murine skin wounds induces a pyoderma gangrenosum-like neutrophilic dermatosis accompanied by spontaneous gut inflammation

S. Jatana, A. K. Ponti, E. E. Johnson, N. A. Rebert, J. L. Smith, C. G. Fulmer, E. V. Maytin, J.-P. Achkar, A. P. Fernandez, C. McDonald

This study develops a murine model of pyoderma gangrenosum with concurrent gut inflammation by inhibiting pyrimidine synthesis in skin wounds.

bioRxiv · Dec 20, 2022Immunology

A 3D printable device allowing fast and reproducible longitudinal preparation of mouse intestines

B. DeLucia, S. Samorezov, M. T. Zangara, R. L. Markley, L. J. Osborn, K. B. Schultz, C. McDonald, J. Claesen

The paper introduces a 3D printable tool for quickly and consistently dissecting mouse intestines, reducing preparation time and improving reproducibility compared to traditional methods.

bioRxiv · Dec 1, 2021Pathology

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

L. J. Osborn, K. Schultz, W. Massey, B. DeLucia, I. Choucair, V. Varadharajan, K. Fung, A. J. Horak, D. Orabi, I. Nemet, L. E. Nagy, Z. Wang, D. S. Allende, N. Sangwan, A. M. Hajjar, , J. Claesen

bioRxiv · Sep 16, 2021Microbiology

Development of a Reproducible Porcine Model of Infected Burn Wounds

S. A.-d. Said, S. Jatana, A. K. Ponti, E. E. Johnson, K. A. Such, M. T. Zangara, M. Madajka, F. Papay, C. McDonald

This paper develops a reproducible porcine model of infected burn wounds to improve pre-clinical studies and therapy evaluation.

bioRxiv · Aug 16, 2021Pathology

Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 play recessive roles in endolysosomal protein digestion during infection

C. McDonald, D. Smith, M. Di Cristina, G. Kannan, Z. Dou, V. B. Carruthers

This study shows that CPL is the dominant protease in Toxoplasma gondii's VAC, while CPB and ASP1 have dispensable roles in protein digestion.

bioRxiv · Nov 8, 2019Microbiology