Author

G. Kannan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:ecology & biodiversity· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

V. B. Carruthers· 5 shared F. Wang· 3 shared M. Di Cristina· 3 shared T. L. Schultz· 3 shared D. Smith· 2 shared I. Coppens· 2 shared M.-H. Huynh· 2 shared P. Thaprawat· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersMicrobiology

V. B. Carruthers

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Translation initiation factor eIF1.2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors

F. Wang, M. J. Holmes, H. J. Hong, P. Thaprawat, G. Kannan, M.-H. Huynh, T. L. Schultz, M. H. Licon, S. Lourido, W. Dong, J. Brito Querido, W. J. Sullivan, S. E. O Leary, V. B. Carruthers

This study identifies eIF1.2 as a regulator of Toxoplasma gondii differentiation by controlling the translation of key bradyzoite factors.

bioRxiv · Nov 3, 2023 · PreprintMicrobiology

Toxoplasma TgATG9 is critical for autophagy and long-term persistence in tissue cysts

D. Smith, G. Kannan, I. Coppens, F. Wang, H. M. Nugyen, A. Cerutti, T. L. B. Schultz, P. Rimple, M. Di Cristina, S. Besteiro, V. B. Carruthers

This study shows that TgATG9 is essential for autophagy and long-term survival of Toxoplasma gondii bradyzoites in tissue cysts.

eLife · Apr 27, 2021Peer-reviewedMicrobiology

Acquisition of Host Cytosolic Protein by Toxoplasma gondii Bradyzoites

G. Kannan, P. Thaprawat, T. L. Schultz, V. B. Carruthers

This study shows that Toxoplasma gondii bradyzoites can internalize host-derived cytosolic mCherry across the cyst wall.

bioRxiv · Sep 11, 2020Microbiology

Elevated CO2 effects on morphology and survival rate in intertidal benthic foraminifera

G. Kannan, S. Ayyappan, K. Peramal

This study examines the effects of reduced seawater pH on survival and morphology of three intertidal benthic foraminifera species under elevated CO2 conditions.

bioRxiv · Nov 15, 2019 · PreprintEcology

Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 play recessive roles in endolysosomal protein digestion during infection

C. McDonald, D. Smith, M. Di Cristina, G. Kannan, Z. Dou, V. B. Carruthers

This study shows that CPL is the dominant protease in Toxoplasma gondii's VAC, while CPB and ASP1 have dispensable roles in protein digestion.

bioRxiv · Nov 8, 2019Microbiology

A role for Toxoplasma gondii chloroquine resistance transporter in bradyzoite viability and digestive vacuole maintenance

G. Kannan, M. Di Cristina, A. J. Schultz, M.-H. Huynh, F. Wang, T. L. Schultz, M. Lunghi, I. Coppens, V. B. Carruthers

This study shows that the Toxoplasma gondii chloroquine resistance transporter (TgCRT) is essential for maintaining the digestive vacuole and bradyzoite viability, suggesting it as a potential target for treating chronic Toxoplasma infection.

bioRxiv · May 24, 2019Microbiology