C. R. Bishop

Tracking inflammation resolution signatures in lungs after SARS-CoV-2 omicron BA.1 infection of K18-hACE2 mice

This study tracks inflammation resolution in lungs of K18-hACE2 mice infected with SARS-CoV-2 omicron BA.1, showing reduced cytokine signatures and increased anti-inflammatory cell types over time.

Microplastics dysregulate innate immunity in the SARS-CoV-2 infected lung

This study shows that microplastics co-delivered with SARS-CoV-2 in mice suppress early innate immune responses but promote a cytokine release syndrome signature later in infection.

Neurovirulence of the Australian outbreak Japanese Encephalitis virus genotype 4 is lower compared to genotypes 2 and 3 in mice and human cortical brain organoids

This study compares the neurovirulence of JEV genotype 4 (JEVNSW/22) with genotypes 2 and 3 in mice and human brain organoids, finding JEVNSW/22 less neurovirulent and more sensitive to type I interferon.

Increased neurovirulence of omicron BA.5 and XBB variants over BA.1 in K18-hACE2 mice and human brain organoids

This study shows that omicron BA.5 and XBB variants are more neurovirulent than BA.1 in mice and human brain organoids, leading to increased brain infection and mortality.

Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity

This study identifies miR-2946-3p and miR-317-3p as regulators of mosquito longevity in response to Wolbachia wAlbB infection.

Microplastic consumption induces inflammatory signatures in the colon and prolongs a viral arthritis

This study shows that microplastic consumption in mice causes mild colon inflammation and prolongs viral arthritis by increasing Th1, NK cell, and neutrophil signatures.