Author

R. George

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Bahrami· 1 shared A. Naranjo· 1 shared A. Pappo· 1 shared A. Purkiss· 1 shared A. S. Ananthan· 1 shared A. Shelat· 1 shared B. Xu· 1 shared C. Jamora· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bahrami

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epi-microRNA mediated metabolic reprogramming ensures affinity maturation

R. Nakagawa, M. Llorian, S. Varsani-brown, P. Chakravarty, J. M. Camarillo, D. Barry, R. George, N. P. Blackledge, G. Duddy, N. L. Kelleher, R. J. Klose, M. Turner, D. P. Calado

This study identifies miR-155's role in metabolic reprogramming of GC-B cells to support affinity maturation under hypoxic conditions.

bioRxiv · Jul 31, 2023Immunology

Mindin is essential for cutaneous fibrogenesis in a new mouse model of systemic sclerosis

I. Rana, S. Kataria, T.-L. Tan, E. Y. Hajam, D. K. Kashyap, D. Saha, J. Ajnabi, S. Paul, S. Jayappa, A. S. Ananthan, P. Kumar, R. F. Zaarour, H. J, R. Samuel, R. George, , C. Jamora

This study identifies Mindin as a key driver of fibrosis in a new mouse model of systemic sclerosis, showing its role in inducing inflammation and collagen production in fibroblasts.

bioRxiv · Jan 26, 2022 · PreprintPathology

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

I. Gori, R. George, A. Purkiss, S. Strohbuecker, R. A. Randall, R. Ogrodowicz, V. Carmignac, L. Faivre, D. Joshi, S. Kjaer, C. S. Hill

This study shows that SGS mutations in SKI prevent its binding to phosphorylated SMAD2/3, leading to SKI stabilization and reduced TGF-β responses.

bioRxiv · Oct 7, 2020Biochemistry

MYCN Amplification and ATRX Mutations are Incompatible in Neuroblastoma

M. Zeineldin, S. Federico, X. Chen, Y. Fan, B. Xu, E. Stewart, X. Zhou, J. Jeon, L. Griffiths, J. Easton, H. Mulder, D. Yergeau, Y. Liu, J. Wu, C. Van Ryn, , M. Dyer

The paper shows that ATRX mutations and MYCN amplification are mutually exclusive in neuroblastoma and lead to synthetic lethality.

bioRxiv · Jul 29, 2018Cancer Biology