Y. K. Gupta

Barley MLA3 recognizes the host-specificity determinant PWL2 from rice blast (M. oryzae)

The paper shows that the barley NLR Mla3 recognizes the rice blast effector PWL2, conferring resistance in a dosage-dependent manner.

The soybean rust pathogen Phakopsora pachyrhizi displays transposable element proliferation that correlates with broad host-range adaptation on legumes

This study sequenced three Phakopsora pachyrhizi genomes, revealing high transposable element content and its correlation with host-range adaptation in legumes.

RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro

This study investigates how the METTL3-METTL14 complex binds and methylates DNA and RNA, revealing distinct preferences for single-stranded DNA and structured RNA.

Conserved secreted effectors determine endophytic growth and multi-host plant compatibility in a vascular wilt fungus

This study identifies conserved fungal effectors that enable multi-host plant colonization and compatibility in the vascular wilt fungus Fusarium oxysporum.

A metal ion orients mRNA to ensure accurate 2'-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome

The paper reports structures of the SARS-CoV-2 nsp16/nsp10 enzyme complex before and after RNA product release, revealing conformational changes and the role of a metal ion in 2'-O methylation of the first nucleotide.

Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus

The paper reports the high-resolution structure of SARS-CoV-2 nsp16/nsp10 complex during mRNA cap methylation, revealing conformational changes and a novel ligand-binding site for antiviral targeting.