Author

S. Peri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 6 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 6 Assay:bulk RNA-seq· 5 Approach:statistical model· 5 Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Research Focus:differential expression· 2

Frequent Co-Authors

K. Q. Cai· 5 shared J. S. Duncan· 3 shared A. M. Kurimchak· 2 shared D. Restifo· 2 shared E. Cukierman· 2 shared I. Astsaturov· 2 shared J. Chernoff· 2 shared J. Franco-Barraza· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCancer Biology

K. Q. Cai

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Automated workflow for the cell cycle analysis of non-adherent and adherent cells using a machine learning approach

K. Hayatigolkhatmi, C. Soriani, E. Soda, E. Ceccacci, O. El Menna, S. Peri, I. Negrelli, G. Bertolini, G. M. Franchi, R. Carbone, S. Minucci, S. Rodighiero

This paper introduces an automated method for analyzing the cell cycle in both adherent and non-adherent cells using machine learning, validated in AML cell lines and drug response testing.

bioRxiv · Dec 21, 2023Cell Biology

Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

A. C. Cannon, K. Budagyan, C. Uribe-Alvarez, A. M. Kurimchak, D. Araiza-Olivera, K. Q. Cai, S. Peri, Y. Zhou, J. S. Duncan, J. Chernoff

This study identifies CDK9 as a novel therapeutic target in RAC1P29S-mutant melanoma and shows that combining CDK9 inhibition with anti-PD-1 therapy enhances tumor suppression.

bioRxiv · Jun 27, 2023 · PreprintCancer Biology

Ribosomal protein control of hematopoietic stem cell transformation through regulation of metabolism.

B. Harris, D. K. Singh, B. Truong, M. Rhodes, R. Price, S. Shinton, M. Verma, B. Aylward, S. P. Fahl, S. R. Sprinkle, S. Aminov, M. Wang, Y. Zhang, J. Perrigoue, R. Kessel, , D. L. Wiest

This study shows that reduced RPL22 expression in hematopoietic stem cells promotes leukemia by altering metabolism and increasing lipid synthesis via Lin28b.

bioRxiv · May 31, 2023Cancer Biology

Identification of SARS-CoV2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

D. Olagnier, E. Farahani, J. Thyrsted, J. B. Cadanet, A. Herengt, M. Idorn, A. Hait, B. Hernaez, A. Knudsen, M. B. Iversen, M. Schilling, S. E. Jorgensen, M. Thomsen, L. Reinert, M. Lappe, , C. K. Holm

The paper identifies NRF2 agonists 4-OI and DMF as inhibitors of SARS-CoV2 replication and inflammatory responses, effective against multiple viruses.

bioRxiv · Jul 16, 2020Microbiology

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma

E. Sementino, Y. Kadariya, M. Cheung, C. W. Menges, Y. Tan, A.-M. Kukuyan, U. Shrestha, S. Karchugina, K. Q. Cai, S. Peri, J. S. Duncan, J. Chernoff, J. R. Testa

This study shows that inactivating Pak2 reduces tumor development in Nf2-deficient mice, suggesting PAK inhibition could be a therapeutic strategy for NF2-deficient cancers.

bioRxiv · Jun 30, 2020 · PreprintCancer Biology

Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblastdriven nutritional support and immunosuppression

R. Francescone, D. Barbosa Vendramini-Costa, J. Franco-Barraza, J. Wagner, A. Muir, A. N. Lau, L. Gabitova, T. Pazina, S. Gupta, T. Luong, N. Shah, D. Rollins, R. Malik, R. Thapa, D. Restifo, , E. Cukierman

This study identifies Netrin G1 as a promoter of pancreatic ductal adenocarcinoma tumorigenesis by enhancing cancer-associated fibroblast-driven metabolic support and immunosuppression.

bioRxiv · May 30, 2020Cancer Biology

Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 As Candidate Therapeutic Target

K. J. Johnson, V. Kumar, A. M. Kurimchak, N. Srivastava, S. Peri, K. Q. Cai, G. M. Mantia-Smaldone, J. S. Duncan

The paper develops a SILAC-based MIB-MS workflow to profile the kinome in endometrial tumors, identifying SRPK1 as a potential therapeutic target.

bioRxiv · Mar 3, 2020Cancer Biology

Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer

L. G. Cornell, S. Peri, D. Restifo, A. Klochkova, T. R. Hartman, A. M. O'Reilly, R. Francescone, J. Franco-Barraza, N. Shah, E. Nicolas, E. A. Handorf, K. Q. Cai, A. Mazitova, I. Sloma, R. Chiaverelli, , I. Astsaturov

The paper shows that cholesterol deprivation activates TGFβ signaling, promoting basal differentiation in pancreatic cancer by stabilizing the TGFβ receptor.

bioRxiv · May 11, 2019 · PreprintCancer Biology