Author

A. E. Tijhuis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

F. Foijer· 3 shared R. Wardenaar· 3 shared D. C. J. Spierings· 2 shared M. Schubert· 2 shared R. Basto· 2 shared S. Gemble· 2 shared A. Damaskou· 1 shared A. de Bruin· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

F. Foijer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions

F. Edwards, G. Fantozzi, A. Y. Simon, J.-P. Morretton, A. Herbette, A. E. Tijhuis, R. Wardenaar, S. Foulane, S. Gemble, D. C. J. Spierings, F. Foijer, O. Mariani, A. Vincent-Salomon, S. Roman-Roman, X. Sastre-Garau, , R. Basto

The paper shows centrosome amplification in ovarian cancer cells primes them for apoptosis and improves chemotherapy response, independent of multipolar divisions and chromosome instability.

bioRxiv · Jul 28, 2023 · PreprintCell Biology

Short-term molecular consequences of chromosome mis-segregation for genome stability

L. Garribba, G. De Feudis, V. Martis, M. Galli, M. Dumont, Y. Eliezer, R. Wardenaar, M. R. Ippolito, D. R. Iyer, A. E. Tijhuis, D. C. Spierings, M. Schubert, S. Taglietti, C. Soriani, S. Gemble, , S. Santaguida

This study shows that aneuploidy can trigger chromosome instability (CIN) by causing DNA replication stress and continuous CIN, leading to genetically diverse cells with varying proliferation abilities.

bioRxiv · Jun 19, 2022Cell Biology

Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

M. Schubert, C. Hong, L. J. Jilderda, M. Requesens-Rueda, A. E. Tijhuis, J. E. Simon, P. L. Bakker, J. Cooper, A. Damaskou, R. Wardenaar, B. Bakker, S. Gupta, A. van den Brink, L. Andrade-Ruiz, M. H. Koster, , F. Foijer

The paper identifies Stat1 inactivation as a mechanism by which aneuploid cancers evade immune surveillance in mice and humans.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology