Author

C. Straub

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Neuroscience· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

Bernardo Luis SabatiniiD· 2 shared E. Colombi· 2 shared P. B. Rainey· 2 shared A. DeMichele· 1 shared A. Hall· 1 shared A. Khan· 1 shared A. M. Storniolo· 1 shared A. M. Thompson· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Bernardo Luis SabatiniORCID

Author profile →

6 papers

Recent·Most cited

Rapid dissemination of host-metabolism-manipulating transposon-like entities via integrative and conjugative elements

E. Colombi, F. Bertels, G. Doulcier, E. McConnell, T. Pichugina, K. H. Sohn, C. Straub, H. McCann, P. B. Rainey

The paper identifies a transposon-like entity in Pseudomonas syringae ICEs that manipulates bacterial metabolism, with a key regulator affecting gene expression and fitness.

bioRxiv · Apr 24, 2023 · PreprintMicrobiology

Lung spatial profiling reveals a T cell signature in COPD patients with fatal SARS-CoV-2 infection

C. X. Yang, M. Tomchaney, M. F. Landecho, B. Recalde, M. M. Oto, J. Zulueta, J. Malo, S. Knoper, M. Contoli, A. Papi, D. Vasilescu, M. Sauler, C. Straub, C. Tan, F. D. Martinez, , F. Polverino

The paper uses spatial transcriptomic and proteomic profiling to analyze lung tissues from COPD patients who died of COVID-19, revealing increased T-lymphocytes and altered immune responses.

bioRxiv · Apr 20, 2022Immunology

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

S. H. Strand, B. Rivero-Gutierrez, K. E. Houlahan, J. A. Seoane, L. M. King, T. Risom, L. A. Simpson, S. Vennam, A. Khan, L. Cisneros, T. Hardman, B. Harmon, F. Couch, K. Gallagher, M. Kilgore, , K Owzar

The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.

bioRxiv · Jun 16, 2021 · PreprintCancer Biology

Population imaging of neural activity in awake behaving mice in multiple brain regions

Kiryl D. Piatkevich, Seth Bensussen, Hua-an Tseng, Sanaya N. Shroff, Violeta G. López-Huerta, Demian Park, Erica Eunjung Jung, Or A. Shemesh, C. Straub, Howard J. Gritton, Michael F. Romano, Emma K. Costa, Bernardo Luis Sabatini, Zhanyan Fu, Edward S. Boyden, Xue Han

The paper introduces a new genetically encoded voltage indicator, SomArchon, enabling high-speed, sensitive neural activity imaging in awake mice across multiple brain regions.

bioRxiv · Apr 23, 2019 · PreprintNeuroscience

Distinct Cortical-Thalamic-Striatal Circuits Through the Parafascicular Nucleus

Gil Mandelbaum, Julián Taranda, Trevor M. Haynes, Daniel R. Hochbaum, Kee Wui Huang, Minsuk Hyun, Kannan Umadevi Venkataraju, C. Straub, Wengang Wang, Keiramarie Robertson, Pavel Osten, Bernardo Luis Sabatini

The paper identifies distinct cortical-thalamic-striatal circuits within the parafascicular nucleus in mice, revealing heterogeneous neurons organized into parallel functional subcircuits.

Neuron · Mar 21, 2019Peer-reviewedNeuroscience

The ecological genetics of Pseudomonas syringae from kiwifruit leaves

C. Straub, E. Colombi, L. Li, H. Huang, M. D. Templeton, H. C. McCann, P. B. Rainey

The paper studies the population structure and genetic diversity of Pseudomonas syringae from kiwifruit leaves during an outbreak, revealing ecological interactions between pathogenic and commensal strains.

bioRxiv · Mar 7, 2018Microbiology