C. Taveneau

Obtaining high-resolution cryo-EM structures using a common LaB6, 120-keV electron microscope equipped with a sub 200-keV optimised direct electron detector.

This paper demonstrates that a standard 120-keV TEM with a direct electron detector can achieve high-resolution cryo-EM reconstructions of various proteins.

Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates

This study uses cryo-electron tomography to reveal that PRC1-CBX8 condensates are porous and dynamic, challenging the notion of rigid chromatin compaction in gene repression.

Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

This study shows that human septins form octamer-based filaments that mediate actin-membrane anchoring, as demonstrated through various imaging and biophysical techniques.

Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

This study isolates recombinant human septin octamers with distinct SEPT9 isoforms and shows they form filament assemblies and bind actin filaments.

Automated cryo-lamella preparation for high-throughput in-situ structural biology

This paper introduces an automated method for preparing cryo-lamellae, increasing throughput from ~10 lamellae/day to 5 lamellae/hour with consistent quality for cryo-ET analysis.

Two polybasic domains of septin9 control septin filaments assembly and Golgi integrity

This study identifies two polybasic domains in septin 9 that mediate interaction with phosphoinositides and are critical for septin filament assembly and Golgi integrity.