Author

M. Mavrakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Iv· 4 shared A. Llewellyn· 3 shared M. Belhabib· 3 shared P. Verdier-Pinard· 3 shared A. Badache· 2 shared A. Bertin· 2 shared C. Taveneau· 2 shared G. Castro-Linares· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersCell Biology

F. Iv

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Author profile →

6 papers

Recent·Most cited

Animal septins contain functional transmembrane domains

J. A. Perry, M. E. Werner, S. Omi, B. W. Heck, P. S. Maddox, M. Mavrakis, A. S. Maddox

The paper identifies a transmembrane domain in septins from C. elegans and primates, showing it is required for membrane association and tissue integrity.

bioRxiv · Nov 20, 2023Cell Biology

Human septins in cells organize as octamer-based filaments mediating actin-membrane anchoring

C. S. Martins, C. Taveneau, G. Castro-Linares, M. Baibakov, N. Buzhinsky, M. Eroles, V. Milanovic, F. Iv, L. Bouillard, A. Llewellyn, M. Gomes, M. Belhabib, M. Kuzmic, P. Verdier-Pinard, S. Lee, , M. Mavrakis

This study shows that human septins form octamer-based filaments that mediate actin-membrane anchoring, as demonstrated through various imaging and biophysical techniques.

bioRxiv · Feb 23, 2022Cell Biology

Septin-microtubule association requires a MAP-like motif unique to Sept9 isoform 1 embedded into septin octamers

M. Kuzmic, G. Castro Linares, J. Leischner Fialova, F. Iv, D. Salaün, A. Llewellyn, M. Gomes, M. Belhabib, Y. Liu, K. Asano, T. Tachibana, G. Koenderink, A. Badache, M. Mavrakis, P. Verdier-Pinard

The paper identifies a MAP-like motif in Sept9 isoform 1 that drives septin-microtubule interaction and shows how HNA mutations disrupt this association.

bioRxiv · Apr 6, 2021 · PreprintCell Biology

4polar-STORM polarized super-resolution imaging of actin filament organization in cells

C. V. Rimoli, C. A. Valades Cruz, V. Curcio, M. Mavrakis, S. Brasselet

The paper introduces 4polar-STORM, a new microscopy method that combines STORM with polarization-resolved imaging to determine single molecule localization and orientation in cells, revealing bimodal actin filament orientations in lamellipodia.

bioRxiv · Mar 17, 2021Biophysics

Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

F. Iv, C. Silva Martins, G. Castro-Linares, C. Taveneau, P. Barbier, P. Verdier-Pinard, L. Camoin, S. Audebert, F.-C. Tsai, L. Ramond, A. Llewellyn, M. Belhabib, K. Nakazawa, A. Di Cicco, R. Vincentelli, , M. Mavrakis

This study isolates recombinant human septin octamers with distinct SEPT9 isoforms and shows they form filament assemblies and bind actin filaments.

bioRxiv · Jan 21, 2021Cell Biology

Membrane binding controls ordered self-assembly of animal septins

A. Szuba, F. Bano, F. Iv, M. Mavrakis, R. P. Richter, A. Bertin, G. H. Koenderink

This study shows membrane binding enables fly septins to form ordered filamentous arrays, with C-terminal regions required for stacking.

bioRxiv · Sep 22, 2020Cell Biology