Author

C. Thiele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2

Frequent Co-Authors

J. Zurkovic· 2 shared K. Hiller· 2 shared A. Gaebler· 1 shared A. Pfeifer· 1 shared A. Z. Samuel· 1 shared B. Gryder· 1 shared B. Hu· 1 shared B. Niemann· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersImmunology

J. Zurkovic

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis

F. J. Graelmann, F. Gondorf, Y. Majlesain, B. Niemann, K. Klepac, M. Gottschalk, M. Mayer, I. Iriady, P. Hatzfeld, S. K. Lindenberg, K. Wunderling, C. Thiele, Z. Abdullah, W. He, K. Hiller, , L. Reverte-Salisa

This study investigates the cell type-specific roles of AhR and AhRR in diet-induced obesity and fibrosis, finding that AhRR deficiency protects from metabolic dysfunction and liver damage, while AhR deficiency worsens outcomes.

Molecular Metabolism · Jul 1, 2024Peer-reviewedImmunology

Anabolic lipid metabolism regulates adipose type 2 innate lymphoid cell differentiation to maintain metabolic health

M. R. Theodorou, J. Yu, F. Nikolka, J. Zurkovic, C. Wientjens, P. Weiss, R. Rombo, F. Karagiannis, C. Thiele, J. Hasenauer, K. Hiller, C. Wilhelm

This study shows that ACC1 regulates adipose ILC2 differentiation and function in obesity, linking lipid metabolism to metabolic health.

bioRxiv · Mar 26, 2024 · PreprintImmunology

BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue

K. Sieckmann, N. Winnerling, D. J. Silva Ribeiro, R. Kardinal, L. M. Steinheuer, G. Schermann, C. Klausen, N. Blank-Stein, J. Schulte-Schrepping, C. Osei-Sarpong, M. Becker, L. Bonaguro, M. Beyer, K. Thurley, H. May-Simera, , D. Wachten

This study shows that primary cilia dysfunction in Bbs8-/- mice reduces adipose stem cells and promotes fibrogenic progenitors via disrupted Hedgehog signaling, affecting adipogenesis and lipid uptake.

bioRxiv · Jan 25, 2024 · PreprintCell Biology

Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation

D. Banerjee, B. Gryder, S. Bagchi, Z. Liu, H.-C. Chen, M. Xu, M. Sun, Z. Vaksman, S. J. Diskin, J. Khan, C. Thiele

This study identifies lineage-specific transcription factors and super-enhancers driving neuroblastoma self-renewal and differentiation using ATRA treatment and CRISPR screening.

bioRxiv · Jul 23, 2020Cancer Biology

Molecular profiling of lipid droplets inside HuH7 Cells with Raman micro-spectroscopy

A. Z. Samuel, R. Miyaoka, M. Ando, A. Gaebler, C. Thiele, H. Takeyama

This study uses Raman micro-spectroscopy with multivariate curve resolution to profile lipid droplet molecular composition in HuH7 cells, revealing structural changes related to cellular physiology.

bioRxiv · Feb 27, 2020Bioengineering

Cholesterol binding to the transmembrane region of a group 2 HA of Influenza virus is essential for virus replication affecting both virus assembly and HA’s fusion activity

B. Hu, C. T. Hoefer, C. Thiele, M. Veit

bioRxiv · Apr 8, 2019Cell Biology