Author

M. R. Patterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Organism:human· 5 Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Macdonald· 5 shared A. Whitehouse· 3 shared E. L. Morgan· 3 shared A. Samson· 2 shared C. W. Wasson· 2 shared D. Barba-Moreno· 2 shared D. Evans· 2 shared J. A. Scarth· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

A. Macdonald

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

M. R. Patterson, A. S. Meijers, E. L. Ryder, J. A. Scarth, D. Evans, A. L. Turner, C. W. Wasson, J. E. Darell, C. D. James, M. Wang, J. E. Ladbury, I. M. Morgan, A. Samson, E. L. Morgan, A. Macdonald

This study shows that HPV E7 represses miR-203, leading to LASP1 upregulation and promoting proliferation in HPV-positive cervical cancer.

bioRxiv · Jan 8, 2024Cancer Biology

m6A regulates the stability of cellular transcripts required for efficient KSHV lytic replication

O. Manners, B. Baquero-Perez, T. J. Mottram, I. D. Yonchev, C. J. Trevelyan, M. R. Patterson, A. Macdonald, S. A. Wilson, J. Aspden, A. Whitehouse

This study shows m6A modification stabilizes GPRC5A mRNA, which promotes KSHV lytic replication by enhancing NF-κB signaling.

bioRxiv · Feb 9, 2023 · PreprintMicrobiology

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

J. A. Scarth, C. W. Wasson, M. R. Patterson, D. Evans, D. Barba-Moreno, H. Carden, A. Whitehouse, J. Mankouri, A. Samson, E. L. Morgan, A. Macdonald

This study shows that HPV exploits KATP channels to promote cervical cancer cell proliferation through MAPK/AP-1 signaling.

bioRxiv · Sep 22, 2022Microbiology

CircHIPK3 dysregulation of the miR-30c/DLL4 axis is essential for KSHV lytic replication

K. L. Harper, T. J. Mottram, C. A. Arene, B. Foster, M. R. Patterson, E. McDonnell, A. Macdonald, D. Westhead, A. Whitehouse

The paper identifies a host ncRNA regulatory network involving circHIPK3 and miR-30c/DLL4 that is essential for KSHV lytic replication in B cells.

bioRxiv · Oct 7, 2021Microbiology

Time scales of mixing in an imperforate scleractinian coelenteron

S. D. Williams, M. R. Patterson

The paper measures mixing time scales in coelentera of corals using oxygen dynamics and electrical network modeling, finding fast mixing and high-frequency fluctuations.

bioRxiv · Sep 3, 2020 · PreprintPhysiology

The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer

E. L. Morgan, M. R. Patterson, D. Barba-Moreno, A. Wilson, A. Macdonald

This study identifies USP13 as an oncogene in cervical cancer that stabilizes Mcl-1, enhancing cell survival and sensitivity to ABT-263.

bioRxiv · Jul 25, 2020Microbiology