G. Volpe

coRIC map: a framework for the exploration of multifaceted subcellular RNA-binding proteins

The paper introduces coRIC map, an experimental and analytical framework to study subcellular RNA-binding protein dynamics and interactions, revealing new functions and stress responses.

Dynamic live/apoptotic cell assay using phase-contrast imaging and deep learning

This paper presents a deep learning method to assess live/apoptotic cell ratios using phase-contrast imaging, avoiding chemical stains and enabling dynamic analysis.

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia

This study shows that Myb insufficiency in mice leads to age-related hematological diseases, suggesting proteostasis disruption as a mechanism.

The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus

This study shows that environmental topography affects multicellular structure formation in Myxococcus xanthus by altering cell motility and aggregation dynamics.

Global Profiling of the Lysine Crotonylome in Different Pluripotent States

This study profiles protein crotonylation in different mouse pluripotent states, identifying 3628 sites and showing that crotonyl-CoA promotes proteasome activity and delays differentiation.

Ablation of MYB-dependent leukaemia phenotype in MLL-driven AML correlates with increased expression of MAFB.

The paper shows that MYB ablation in MLL-driven AML increases MAFB expression, while this effect is absent in AML with complex karyotypes.

Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

This study creates a single-cell transcriptome atlas of a non-human primate to explore SARS-CoV-2 targets and immune responses, identifying potential therapeutic targets and mechanisms linking IL6 to viral entry.

Chemotactic synthetic vesicles: design and applications in blood brain barrier crossing

This paper designs synthetic vesicles that exhibit chemotaxis by converting glucose, showing improved brain penetration compared to non-chemotactic systems.