Author

Cameron J. Koch

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Adham Sean BeariD· 1 shared Andrea FacciabeneiD· 1 shared Annemarie LangiD· 1 shared Beatriz M. CarrenoiD· 1 shared Constantinos KoumenisiD· 1 shared Eric S. DiffenderferiD· 1 shared Ernestina SchipaniiD· 1 shared Francesca CostabileiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

Adham Sean BearORCID

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Author profile →

3 papers

Recent·Most cited

Decreased Damage for proton FLASH vs Conventional Dose Rates in Mouse Jejunum Shown by Quantitative Assessment of γ-H2AX

Najah Curtis, Michele M. Kim, Ioannis I. Verginadis, Wei Zou, Eric S. Diffenderfer, Constantinos Koumenis, Cameron J. Koch, Rodney D. Wiersma

This study compares DNA damage in mouse jejunum after FLASH and conventional proton irradiation, finding FLASH reduces DNA damage even in hypoxic regions, suggesting oxygen-independent sparing effects.

bioRxiv · Sep 18, 2026 · PreprintBiophysics

Tumor-to-endothelium mitochondrial transfer licenses endothelial cells for CD8+ T cell recognition via mitochondrial neoantigen presentation

Francesca Costabile, Stefano Pierini, Renzo F. Perales-Linares, Nektaria Maria Leli, Adham Sean Bear, Cameron J. Koch, Beatriz M. Carreno, M T Lotze, Larry N. Singh, Marny Falck, Andrea Facciabene

This study shows that vaccinating against tumor-associated mitochondrial antigens enhances CD8+ T cell recognition of endothelial cells, improving immune response and survival in RCC models.

bioRxiv · Feb 2, 2026 · PreprintCancer Biology

Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche

Annemarie Lang, Joseph M. Collins, Madhura P. Nijsure, Simin Belali, Mohd Parvez Khan, Yasaman Moharrer, Ernestina Schipani, Yvette Y. Yien, Yi Fan, Michael Gelinsky, Sergei A. Vinogradov, Cameron J. Koch, Joel D. Boerckel

This study shows that erythroid precursors in the bone marrow increase local oxygen levels after injury, promoting tissue repair by enhancing angiogenesis and osteogenesis.

Proceedings of the National Academy of Sciences · Nov 11, 2025Peer-reviewedCell Biology