Author

Carsten Russ

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Daniel J. Ho· 2 shared Kathleen A. WorringeriD· 2 shared Robert J. IhryiD· 2 shared Ajamete KaykasiD· 1 shared Alicia Lindeman· 1 shared Brian Kelly· 1 shared Caroline Gubser KelleriD· 1 shared Chaoyang YeiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Daniel J. Ho

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Author profile →

2 papers

Recent·Most cited

DRUG-seq Provides Unbiased Biological Activity Readouts for Drug Discovery

Jingyao Li, Daniel J. Ho, Martin Hénault, Chian Yang, Marilisa Neri, Robin Ge, Steffen Renner, Leandra Mansur, Alicia Lindeman, Brian Kelly, Tayfun Tumkaya, Xiaoling Ke, Gilberto J Soler-Llavina, Gopi Shanker, Carsten Russ, , Robert J. Ihry

DRUG-seq provides high-throughput, unbiased transcriptomic data for drug discovery, demonstrating reproducibility and mechanism-of-action resolution for diverse compounds.

ACS Chemical Biology · May 4, 2022Peer-reviewedGenomics

P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells

Robert J. Ihry, Kathleen A. Worringer, Max R. Salick, Elizabeth Frias, Daniel J. Ho, Kraig M. Theriault, Sravya Kommineni, Julie Chen, Marie Sondey, Chaoyang Ye, Ranjit Randhawa, Tripti Kulkarni, Zinger Yang, Gregory McAllister, Carsten Russ, , Ajamete Kaykas

This study shows that CRISPR/Cas9 induces toxicity in human pluripotent stem cells, which is dependent on TP53 and hinders genome engineering.

Nature Medicine · Jun 8, 2018Peer-reviewedMolecular Biology