Author

Sravya Kommineni

Novartis (Switzerland)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:CRISPR screen· 2 Research Focus:drug response / drug discovery· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Daniel J. Ho· 3 shared Kathleen A. WorringeriD· 3 shared Ajamete KaykasiD· 2 shared Brant K. PetersoniD· 2 shared Federica PiccioniiD· 2 shared Jana M. MitchelliD· 2 shared Joseph J. RaymondiD· 2 shared Karrie Chan· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Daniel J. Ho

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Natural variation in gene expression and Zika virus susceptibility revealed by villages of neural progenitor cells

Michael F. Wells, James C. Nemesh, Sulagna Dia Ghosh, Jana M. Mitchell, Curtis J. Mello, Daniel Meyer, Kavya Raghunathan, Matthew Tegtmeyer, Derek Hawes, Anna Neumann, Kathleen A. Worringer, Joseph J. Raymond, Sravya Kommineni, Karrie Chan, Daniel J. Ho, , Steven A. McCarroll

The paper identifies a common genetic variant in IFITM3 that explains most inter-individual variation in neural progenitor cell susceptibility to Zika virus using natural genetic variation and synthetic perturbations.

bioRxiv · Nov 8, 2021 · PreprintGenomics

Genome-wide screens in accelerated human stem cell-derived neural progenitor cells identify Zika virus host factors and drivers of proliferation

Michael F. Wells, Max R. Salick, Federica Piccioni, Ellen J. Guss, Jana M. Mitchell, Kathleen A. Worringer, Joseph J. Raymond, Sravya Kommineni, Karrie Chan, Daniel J. Ho, Brant K. Peterson, Marco T. Siekmann, Olli P. H. Pietiläinen, Ralda Nehme, Ajamete Kaykas, Kevin C. Eggan

bioRxiv · Nov 22, 2018 · PreprintNeuroscience

P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells

Robert J. Ihry, Kathleen A. Worringer, Max R. Salick, Elizabeth Frias, Daniel J. Ho, Kraig M. Theriault, Sravya Kommineni, Julie Chen, Marie Sondey, Chaoyang Ye, Ranjit Randhawa, Tripti Kulkarni, Zinger Yang, Gregory McAllister, Carsten Russ, , Ajamete Kaykas

This study shows that CRISPR/Cas9 induces toxicity in human pluripotent stem cells, which is dependent on TP53 and hinders genome engineering.

Nature Medicine · Jun 8, 2018Peer-reviewedMolecular Biology