Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast
Jannik Zimmermann, Lukas Lang, Gaetano Calabrese, Hugo Laporte, Prince Saforo Amponsah, Christoph Michalk, Tobias Sukmann, Julian Oestreicher, Anja Tursch, Esra Peker, Theresa N E Owusu, Matthias Weith, Letícia Prates Roma, Marcel Deponte, Jan Riemer, Bruce Morgan
This study identifies Tsa1 as the primary peroxide scavenger in yeast and shows it can generate GSSG under H2O2 conditions.
Free Radical Biology and Medicine · Nov 6, 2024Peer-reviewedBiochemistry