Author

Matthias Weith

University of CologneORCID 0000-0003-0804-4262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas BeyeriD· 1 shared Anja TurschiD· 1 shared Bruce MorganiD· 1 shared Christoph Michalk· 1 shared Christopher Thomas WorkmaniD· 1 shared Esra PekeriD· 1 shared Gaetano CalabreseiD· 1 shared Hugo LaporteiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Andreas BeyerORCID

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2 papers

Recent·Most cited

Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast

Jannik Zimmermann, Lukas Lang, Gaetano Calabrese, Hugo Laporte, Prince Saforo Amponsah, Christoph Michalk, Tobias Sukmann, Julian Oestreicher, Anja Tursch, Esra Peker, Theresa N E Owusu, Matthias Weith, Letícia Prates Roma, Marcel Deponte, Jan Riemer, Bruce Morgan

This study identifies Tsa1 as the primary peroxide scavenger in yeast and shows it can generate GSSG under H2O2 conditions.

Free Radical Biology and Medicine · Nov 6, 2024Peer-reviewedBiochemistry

Large-scale changes of molecular network states explain complex traits

Matthias Weith, Jan Großbach, Mathieu Clément‐Ziza, Ludovic C. J. Gillet, Maria Rodríguez‐López, Samuel Marguerat, Christopher Thomas Workman, Paola Picotti, Jürg Bähler, Ruedi H. Aebersold, Andreas Beyer

The paper identifies a central state transition in yeast molecular networks linked to PKA and TOR signaling, showing how genetic variants can cause global or local molecular changes affecting multiple cellular traits.

bioRxiv · Dec 5, 2022 · PreprintSystems Biology