Shih‐Ting Wang

Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interception

The paper identifies caspase-1 as a target for lung cancer interception by analyzing protease activity in a murine model and showing reduced tumor formation with combined IL-1b and caspase-1 inhibition.

Engineering Multiplexed Synthetic Breath Biomarkers as Diagnostic Probes

This paper engineers multiplexed synthetic breath biomarkers to detect disease-specific protease activities and applies them to diagnose lung cancer and monitor treatment response in mice.

An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies

A DNA-binding agent increases cfDNA levels in blood, improving ctDNA detection and cancer sensitivity in mice.

A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies

A nanoparticle priming agent increases cfDNA levels in blood, improving ctDNA detection sensitivity in tumor-bearing mice.