Author

Zhenyi An

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Carmen Martin-AlonsoiD· 3 shared John Christopher LoveiD· 3 shared Kan XiongiD· 3 shared Sahil PateliD· 3 shared Sangeeta N. BhatiaiD· 3 shared Shervin TabriziiD· 3 shared Timothy BlewettiD· 3 shared Viktor A. AdalsteinssoniD· 3 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Carmen Martin-AlonsoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular determinants of antibody-mediated priming to enhance detection of ctDNA

Shervin Tabrizi, Claire Sullivan, Kasturi Chakraborty, Carmen Martin-Alonso, Zhenyi An, Lily Gao, Daniel M. Kim, Savan K. Patel, Timothy Blewett, Justin Rhoades, Ruolin Liu, Sahil Patel, Kan Xiong, Andjela Crnjac, Sangeeta N. Bhatia, , John Christopher Love

This paper identifies molecular features of monoclonal antibodies that enhance ctDNA detection by increasing its concentration in blood.

bioRxiv · Jan 29, 2026 · PreprintBioengineering

An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies

Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio A. Rodriguez‐Aponte, Christopher A. Naranjo, Shih‐Ting Wang, Douglas Shea, Todd R. Golub, Sangeeta N. Bhatia, Viktor A. Adalsteinsson, John Christopher Love

A DNA-binding agent increases cfDNA levels in blood, improving ctDNA detection and cancer sensitivity in mice.

bioRxiv · Jan 13, 2023 · PreprintGenomics

A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies

Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sahil Patel, Zhenyi An, Sainetra Sridhar, Ahmet Bekdemir, Douglas Shea, Ava P. Amini, Shih‐Ting Wang, Jesse D. Kirkpatrick, Justin Rhoades, Todd R. Golub, John Christopher Love, , Sangeeta N. Bhatia

A nanoparticle priming agent increases cfDNA levels in blood, improving ctDNA detection sensitivity in tumor-bearing mice.

bioRxiv · Jan 13, 2023 · PreprintGenomics