Jonna B. Westover

Immunomodulatory RIG-I Agonist SLR14 Confers Protection Against a Range of Highly Pathogenic Negative Sense RNA viruses

SLR14, an immunomodulatory RIG-I agonist, provides broad-spectrum antiviral protection against multiple highly pathogenic negative-sense RNA viruses in vitro and in vivo.

Mutations that positively affect Bandavirus glycoprotein function on VSV vectored vaccines

This paper identifies a mutation that enhances the efficacy of a VSV-based vaccine against SFTSV and develops a similar vaccine for HRTV, showing improved immune responses and protection.

Development of Broad-spectrum β-cyclodextrins-Based Nanomaterials Against Influenza Viruses

This study develops CD-SA, a β-cyclodextrin-based nanomaterial that acts as a potent broad-spectrum antiviral against influenza A and B viruses, showing higher efficacy than Oseltamivir in ex vivo and in vivo tests.

In Vitro Analysis of the Anti-viral Potential of nasal spray constituents against SARS-CoV-2

This study tests the in vitro anti-viral effect of a nasal spray containing xylitol and grapefruit seed extract against SARS-CoV-2, finding a significant reduction in virus titer.