Chemical-Genetic Interrogation of Nuclear Size Control Reveals Cancer-Specific Effects on Cell Migration and Invasion
A. Rizzotto, S. Tollis, N. T. Pham, J. Wildenhain, N. Zuleger, J. T. Keys, D. Batrakou, J. Culley, S. Zheng, J. Lammerding, N. O. Carragher, V. Brunton, M. Auer, M. Tyers, E. C. Schirmer
The paper identifies compounds that reverse nuclear size changes in cancer cell lines and finds they inhibit cell migration and invasion.
bioRxiv · Jan 10, 2020 · PreprintCancer Biology