Author

J. T. Keys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:wet-lab / biochemical assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Lammerding· 2 shared A. Rizzotto· 1 shared B. C. H. Cheung· 1 shared D. Batrakou· 1 shared E. C. Schirmer· 1 shared J. Culley· 1 shared J. Wildenhain· 1 shared M. A. Elpers· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

J. Lammerding

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Author profile →

2 papers

Recent·Most cited

Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior

J. T. Keys, B. C. H. Cheung, M. A. Elpers, M. Wu, J. Lammerding

The paper identifies rear cortex contraction as a mechanism that increases intracellular pressure to facilitate nuclear transit during confined cell migration.

bioRxiv · Sep 10, 2022Cell Biology

Chemical-Genetic Interrogation of Nuclear Size Control Reveals Cancer-Specific Effects on Cell Migration and Invasion

A. Rizzotto, S. Tollis, N. T. Pham, J. Wildenhain, N. Zuleger, J. T. Keys, D. Batrakou, J. Culley, S. Zheng, J. Lammerding, N. O. Carragher, V. Brunton, M. Auer, M. Tyers, E. C. Schirmer

The paper identifies compounds that reverse nuclear size changes in cancer cell lines and finds they inhibit cell migration and invasion.

bioRxiv · Jan 10, 2020 · PreprintCancer Biology